The Margaree River (Abhainn Mhargaraidh) is a river on Cape Breton Island in Nova Scotia. The northeast branch of the river derives from the watershed of the Cape Breton Highlands, while the Southwest Margaree flows northeast from Lake Ainslie. The two branches join at Margaree Forks. The river then flows north to empty into the Gulf of Saint Lawrence at Margaree Harbour, Nova Scotia. The river is 120 km in length and drains an area of 1,375 km². The Margaree has been well known for a century for its trout and Atlantic salmon sport fishery, that draws anglers from near and far. Fishing is highly regulated now and is restricted to fly fishing only, with barbless hooks, in the main stem of the river.