Cities in Commonwealth of Pennsylvania, United States ( 562 )
- Sanatoga
- Saw Creek
- Sayre, Pennsylvania
- Schlusser
- Schnecksville
- Schuylkill Haven
- Scottdale, Pennsylvania
- Scranton
- Selinsgrove
- Sellersville
- Seven Fields
- Sewickley, Pennsylvania
- Shamokin, Pennsylvania
- Shanor-Northvue
- Sharon Hill, Pennsylvania
- Sharon, Pennsylvania
- Sharpsburg, Pennsylvania
- Sharpsville, Pennsylvania
- Shenandoah, Pennsylvania
- Shillington, Pennsylvania
- Shiloh, Pennsylvania
- Shiloh, Pennsylvania
- Shippensburg
- Shrewsbury, Pennsylvania
- Sinking Spring, Pennsylvania
- Skippack, Pennsylvania
- Skyline View
- Slatington, Pennsylvania
- Slippery Rock, Pennsylvania
- Somerset, Pennsylvania
- Souderton
- South Park Township
- South Williamsport
- Spring City, Pennsylvania
- Spring House, Pennsylvania
- Springdale, Pennsylvania