Pardubice (Czech pronunciation: [ˈpardubɪtsɛ]; German: Pardubitz) is a city in the Czech Republic. It is the capital city of the Pardubice Region and lies on the river Elbe, 96 kilometres east of Prague. There is an old Tower and a Castle. Factories include the Synthesia chemical factory (manufacturer of Semtex, a plastic explosive), an oil refinery Paramo, a heavy machinery factory and an electronic equipment plant.