Simpsonville is a city in Greenville County, South Carolina, United States. It is part of the Greenville–Mauldin–Easley Metropolitan Statistical Area. The population was 18,244 at the 2010 census, and estimated at 19,056 in 2012. Simpsonville is part of the "Golden Strip", along with Mauldin and Fountain Inn, which is noted for having low unemployment due to a diversity of industries including Para-Chem, Kemet, and Milliken. Simpsonville is home to Hillcrest High School.