Leesburg is a city in Lee County, Georgia, United States. The population was 2,896 at the 2010 census. The city is the county seat of Lee County and is part of the Albany, Georgia Metropolitan Statistical Area. The area was an important center for the study of malaria in 1924. A graduate student named Lowell T. Coggeshall collected anopheline larvae in a swamp near Leesburg. Later he helped mastermind the U.S.