Umapine (pronounced U-mah-pine) is a census-designated place and unincorporated community in Umatilla County, Oregon, United States, two miles from the Oregon-Washington border. It has a population of 315 people as of 2010. The community is part of the Pendleton–Hermiston Micropolitan Statistical Area. It was established as a railroad stop on the Walla Walla Valley Railway with an active lumber yard and large population of dairies in the early 1900s. The current economy is supported by agriculture, including wheat and hay farms, apple orchards, and an increasing number of vineyards.