Tuluá (pronounced /toolu-wA/ ) is a city located in the heart of the Cauca Valley, Colombia Valle del Cauca, Colombia. A major industrial and commercial center, it is the region's fourth largest city after Cali, the department capital, Buenaventura and Palmira. Founded around 1741 by Juan de Lemos y Aguirre, it has a population of approximately 200,000 inhabitants.