The Uyu River, also pronounced Uru River (Uyu Chaung in Burmese), is a river in northern Myanmar, formerly Burma. It is a major tributary of the Chindwin River, itself the largest tributary of the country's chief river, the Ayeyarwady. Its source lies in the Hukawng Valley of Kachin State, and it takes a southwesterly course through a fertile and well irrigated valley.