Sameakki Mean Chey District (Khmer: ស្រុកសាមគ្គីមានជ័យ) is a district (srok) in the south of Kampong Chhnang Province, in central Cambodia. The district capital is Sameakki Mean Chey town located on the rail line some 52 kilometres south of the provincial capital of Kampong Chhnang by road. The district shares a border with Kandal and Kampong Speu provinces to the south.