Perry Creek is a 28.9-mile-long (46.5 km) tributary of the Missouri River in the state of Iowa. It rises in central Plymouth County and flows generally to the south-by-southwest, crossing the Woodbury County line at the city limits of Sioux City, north of Briar Cliff University and the Sioux City Country Club. At about Tenth Street, the creek enters a conduit near (42.500°N 96.409°W), which then takes the flow underground to its mouth at the Missouri on the western edge of the downtown riverfront area.