Buffalo is an unincorporated community and census-designated place (CDP) in southern LaRue County, Kentucky, United States. Its population was 498 as of the 2010 census. It lies along Kentucky Route 61 south of the city of Hodgenville, the county seat of LaRue County. Its elevation is 748 feet (228 m), and it is located at (37°30′43″N85°41′55″W) (37.5120048, -85.6985728).